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Without ATP, what can muscles not do?

  1. Use Krebs Cycle

  2. Contract or relax

  3. Use fats as energy

  4. Use proteins as energy

The correct answer is: Contract or relax

Muscle function heavily relies on adenosine triphosphate (ATP), the primary energy carrier in cells. Without ATP, muscles are unable to perform the fundamental processes required for contraction and relaxation. This is because muscle contractions occur through a cycle of interactions between actin and myosin filaments, which require ATP to enable the myosin heads to detach from actin and re-cock for the next contraction. Additionally, ATP is necessary for pumping calcium ions back into the sarcoplasmic reticulum, which is essential for muscle relaxation. While the other options mention metabolic processes and energy usage, they do not directly address the immediate physiological need for muscle movement. In particular, the Krebs Cycle (also known as the citric acid cycle) is a crucial metabolic pathway for energy production but does not itself trigger muscle contraction. The utilization of fats and proteins for energy involves complex metabolic pathways that can occur independently of immediate muscle function. Therefore, without ATP, muscles lose the ability to contract or relax, highlighting the critical role of this molecule in muscle physiology.